产品货号：
Z17203
中文名称：
GLI2抗体
英文名称：
Anti-GLI2 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLI2 Antibody |
| 指标别名 | GLI family zinc finger 2;CJS;HPE9;PHS2;THP1;THP2;GLI2 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | ELISA,IHC,WB |
| 基因名称 | GLI2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids from an internal region of Mouse Gli-2. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against mouse Gli-2 protein.The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.A BLAST analysis was used to suggest cross-reactivity with Gli-2 from mouse and rat sources based on 100% sequence homology with the immunogen.Reactivity with Gli-2 from other sources is not known. |
| 浓度 | 1.02mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Gli-2 (also known as Zinc Finger Protein Gli-2,GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family.Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs.These motifs contain conserved H-C links.Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling,and they are implicated as potent oncogenes in the embryonal carcinoma cell.The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression.Gli-2 is also thought to play a role during embryogenesis.The encoded protein is associated with several phenotypes:Greig cephalopolysyndactyly syndrome,Pallister-Hall syndrome,pre-axial polydactyly type IV,and postaxial polydactyly types A1 and B.Anti-Gli 2 Antibody is useful for researchers interested in transcription factor activities,DNA binding,and chromatin binding research. |
| Uniprot ID | Q8K0K3 |
| 推荐稀释比 | ELISA:1:15,000 - 1:60,000 IHC:2μg/mL to 20μg/mL WB:1:500 - 1:2,000 |
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